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The Manchester City man has pulled out of Ghana's AFCON qualifiers to get treatment on a swollen leg.
Ghana's boss told Kudus to rest after the Tottenham forward's latest cameo raised fears of a setback.
After 28 caps and two World Cups, Inaki Williams has called time on his Ghana career.
Two months after stepping down, the veteran boss returns to lead the Black Stars again.
Colombia reached the last 16 of the World Cup for the third time in their last three appearances at the tournament with a 1-0 win over Ghana.